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Ketogenic Diet and Muscle Metabolism
The ketogenic diet significantly alters metabolic physiology, and this underlies the therapeutic effects of the diet on seizure control, glycemic management and weight loss. There are a variety of metabolic and signaling mechanisms associated with ketosis that are reported in the scientific...
Should you exercise on an empty stomach? Part 2
In our previous blog (part 1), we introduced the concept of fasted exercise, which is essentially just exercising before having eaten anything following an overnight fast, or skipping breakfast entirely. In that blog, we covered how exercising in the fasted state may influence body weight and...
Should you exercise on an empty stomach? Part 1
If you spend any time on social media, you’ve likely come across recommendations to work out fasted to burn more fat. On the other hand, there’s people who might make you feel like you absolutely need to eat before you hit the gym, otherwise you’re going to lose all your muscle and feel dead. Not...
Beta-hydroxybutyrate and Cardiovascular Health
When we think of ketones or ketogenic diets, most people think of brain health, seizure control, sports performance, or as a diet therapy for cancer management, but the heart thrives on fatty acids and ketones. Probably because ketones are used by the mitochondria to generate ATP and mitochondrial...
Metabolic Health Immersion for Medical Education
A new paper, published in the American Journal of Lifestyle Medicine by a group at Harvard Medical School and Harvard School of Dental Medicine, reports on the results of a pilot program using Continuous Glucose Monitors (CGMs) as part of a Metabolic Immersion program. After being trained in the...
Why do we need both D-BHB and L-BHB?
Ketones are produced by the liver under conditions of low glucose availability for extended periods of time, such as a prolonged fast (24-hours+) or days on a very low carbohydrate ketogenic diet. An elevation of ketone bodies is what defines ketosis. In ketosis we are producing three different...
Untangling LDL-C Elevation in Lean Mass Hyper Responders (LMHR) on a Ketogenic Diet
A series of papers published in the journals Current Developments in Nutrition, Frontiers in Endocrinology, and Metabolites are beginning to shed light on a ketogenic diet-induced alteration in cardio-metabolic biomarkers that has come to be known as Lean Mass Hyper Responders (LMHR). LMHR are...
HIIT: Science and Application
Muscle health is critical for metabolic health, and nothing improves and protects muscle health quite like exercise. Despite the overwhelming health benefits of exercise, it is clear that adults have a very difficult time adhering to regular physical activity. Unfortunately, the pandemic made...
Ketogenic Metabolic Therapy – a very interesting adjuvant treatment for cancer patients
Ketogenic Metabolic Therapy. The patients of these three case reports were seen in The Clinic Integrated Medicine, a Medical private clinic in Belo Horizonte, Brazil. All patients were personally treated by me and my multidisciplinary team. Case 1- Stage IV Breast Cancer Treated with Ketogenic...
BHB and colorectal cancer
Recently, a study published in Nature from the Perelman School of Medicine at the University of Pennsylvania found that the ketone body, beta-hydroxybutyrate (BHB) appears to slow the growth of colorectal cancer in mice. Colorectal cancer is one of the most common forms of cancer, and in the US,...
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