Blog
The Gut-Brain Axis
A gut feeling: Why your stomach hurts when you're nervous Imagine the scenario: you are about to present an important talk on a stage with big, bright lights and lots of people in the audience. Suddenly, moments before you step on stage, you get nervous. We’ve all been there- despite months of...
What is Keto?
What is Ketosis? Ketosis is the metabolic state defined by elevation of ketone bodies. It’s generally accepted that one is in ketosis when blood levels of the primary ketone body, beta-hydroxybutyrate (BHB), reach above 0.5 mmol/L. With the exception of ketosis induced via exogenous ketone...
Dr. Dominic D’Agostino’s favorite books
Here is a short list of great books I have read over the last year. No matter how busy we get it is important to keep learning and growing, and that why I have posted about previous books in the past. I tend to select books related to current and emerging work projects, but also spend several...
The Importance of Metabolic Health for Women’s Health
We previously wrote about the ketogenic diet for women, which we recommend you check out if you’re wondering how the ketogenic diet may differ for men and women. Research has and continues to show how much benefit anyone can gain from a ketogenic diet to restore and support their metabolic health,...
Understanding Non-Alcoholic Fatty Liver Disease
This blog takes a step back and further defines NAFLD and the associated work we are doing in our current clinical trial (NCT04920058) on non-diabetics. This ongoing research reminded us how ubiquitous this condition is and how it can advance without any overt signs detected in standard...
Bipolar Disorder Treatment: Choosing the Right Treatment
Have you ever come across a person diagnosed with bipolar disorder? They experience moments of manic or hypomanic episodes and depression. There are three types of bipolar disorders[1], namely Bipolar 1 disorder, Bipolar 2 disorder, and Cyclothymic disorder. Bipolar 1 disorder: a person with...
Metabolic Flexibility
By now, you are likely in the know of how important insulin sensitivity is to our overall metabolic health and longevity. Insulin resistance essentially precedes type-2 diabetes, and is tightly linked with obesity and metabolic inflexibility. Metabolic inflexibility is thought to contribute to the...
Ketogenic Diet in Substance Abuse
Though ketogenic diet treatment may have a role in a number of substance use disorders (SUDs), so far most studies have addressed the role of keto diets with respect to alcohol abuse. Alcohol Use Disorder (AUD), also known as alcoholism or alcohol dependence, is characterized by strong cravings,...
How do ketones work?
We know from previous studies that our brain metabolism can readily use ketone bodies as a primary source of fuel for the brain. What is more, it is widely accepted that ketone bodies (e.g., βHB), are not only a potential energy source for different tissues of the body, but also potent signaling...
Breath Ketone Measurement: a tool for Metabolic Optimization
In previous posts we have covered the many benefits of nutritional (or fasting ketosis) for things like brain health, improving metabolic biomarkers, reducing pain, and even cancer management. Since our metabolic response to ketogenic diets and fasting varies considerably, it becomes even more...
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