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Why do we need both D-BHB and L-BHB?

Ketones are produced by the liver under conditions of low glucose availability for extended periods of time, such as a prolonged fast (24-hours+) or days on a very low...

HIIT: Science and Application

Muscle health is critical for metabolic health, and nothing improves and protects muscle health quite like exercise. Despite the overwhelming health benefits of exercise, it is...
Biological Sex Differences in Metabolism

Biological Sex Differences in Metabolism

Metabolism is the intricate network of biochemical processes that occur within living organisms to sustain life, and it exhibits fascinating differences between males and females. Emerging evidence highlights the critical role of sex in influencing metabolic processes, including energy...

Why Sodium May Not be Bad for You

Why Sodium May Not be Bad for You

Sodium is an essential mineral that plays a number of important roles in the body. It helps to regulate blood pressure, fluid balance, and muscle and nerve function. While too much sodium can be harmful, there is some evidence to suggest that a moderate amount of sodium in the diet is not...

New Studies Question the Amyloid Cascade Hypothesis of Alzheimer’s 

New Studies Question the Amyloid Cascade Hypothesis of Alzheimer’s 

Despite billions of dollars spent and decades of research, the exact cause of Alzheimer’s is still unknown, and more than 400 clinical trials have failed to produce a meaningful treatment. In 1906, Dr. Alois Alzheimer presented brain autopsy findings on his patient, fifty-one-year-old Auguste...

Can Ketones help during Anesthesia?

Can Ketones help during Anesthesia?

General anesthetic drugs (GAD) are essential in medical practice as they make surgical procedures possible in the absence of pain and consciousness. However, there are adverse effects and toxicities involved with inhaled anesthetics including nephrotoxicity, hepatotoxicity, cardiac arrhythmias,...

Fatty Liver and Metabolic Health

Fatty Liver and Metabolic Health

What does the liver do? The liver is an important metabolic organ that performs over 500 functions. It receives and processes all of the blood leaving the stomach and intestines. It can break down alcohol and metabolize drugs into forms that can be easily put to use by the body. The liver...

Heat and Cold Therapy

Heat and Cold Therapy

HEAT THERAPY There is a long cultural history of sauna use, but recently it has been gaining popularity as a way to improve physical health, mental health and longevity. Unfortunately, when it comes to hard outcomes, most of the research stems from observational data. That said, there are many...

Metabolic Factors of Brain Cancer Management

Metabolic Factors of Brain Cancer Management

Glioblastoma (GBM), is one of the most aggressive types of cancer that can occur in the brain or spinal cord. This cancer has among the highest mortality rates for primary brain tumors. Most diagnoses last for 11-15 months, with few reports of patients surviving past 30 months of diagnosis. While...

Muscle Mass and Cognitive Decline

Muscle Mass and Cognitive Decline

There is a large body of evidence which makes the case for exercise being an important factor for improving longevity, healthspan, and cognitive function. Additionally, there is a strong association for the prevalence of dementia in older adults who have sarcopenia (age-related muscle loss). The...

Clearly Keto – book teaser

Clearly Keto – book teaser

Clearly Keto for Healthy Brain Aging and Alzheimer’s Prevention By Mary T. Newport, MD Foreword by Dominic D’Agostino, PhD and Milene Brown, PhD Release Date November 29, 2022 Did you know that modifiable lifestyle risk factors, like diet and exercise, appear to account for least 30% of dementia...

Ketogenic Diet and Muscle Metabolism

Ketogenic Diet and Muscle Metabolism

The ketogenic diet significantly alters metabolic physiology, and this underlies the therapeutic effects of the diet on seizure control, glycemic management and weight loss. There are a variety of metabolic and signaling mechanisms associated with ketosis that are reported in the scientific...

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